Modifying Enzymes
Amsbio LLC Heparanase Assay Kit Positive Control Enzyme
Measure enzyme activity of heparanase in cell culture supernatants, human plasma, biological fluids and tissue samples. These kits provide a solution to the performance and standardization problems found with traditional measurement techniques used for these types of enzymes.
Medchemexpress LLC TC-Mps1-12 | 1206170-62-8 | 99.8% | 324.38 | 100 MG
TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. It inhibits the growth of pMps1 cell lines and A549 cells in a dose-dependent manner, exhibiting good pharmacokinetic properties.
- Potent and selective Mps1 inhibitor
- Inhibits the growth of pMps1 cell lines with IC50 values of 131 nM in autophosphorylation assay
- Inhibits the growth of A549 cells in a dose-dependent manner in vivo, showing 47% tumor growth inhibition at 100 mg/kg without body weight loss
- Exhibits good PK properties with a Cmax of 3542 ng/mL and AUC of 6604 ng h/mL at an oral dose of 25 mg/kg
Sigma Aldrich Fine Chemicals Biosciences Proteinase from Aspergillus melleus Type XXIII, >=3 units/mg solid | 9001-92-7 | MFCD00132092 | 5G
Proteinase from Aspergillus melleus Type XXIII, >=3 units/mg solid | 9001-92-7 | MFCD00132092 | 5G
Sigma Aldrich Fine Chemicals Biosciences Proteinase K from Tritirachium album Reagents designed and manufactured under current ISO 13485 certification. | 39450-01-6 | MFCD00132129 | 5ML
Proteinase K from Tritirachium album Reagents designed and manufactured under current ISO 13485 certification. | 39450-01-6 | MFCD00132129 | 5ML
Sigma Aldrich Fine Chemicals Biosciences Carboxypeptidase A from bovine pancreas (Type II-PMSF treated), >=20 units/mg protein | 11075-17-5 | MFCD00130718 | 500UN
Carboxypeptidase A from bovine pancreas (Type II-PMSF treated), >=20 units/mg protein | 11075-17-5 | MFCD00130718 | 500UN
Cayman Chemical Decnoyl-Coenzyme Ahydrate 10mg
A thioester of decanoic acid and CoA; inhibits the activity of mitochondrial CS and GDH isolated from rat brain (IC50s = 437 and 420 µM, respectively); inhibits FadR from binding its promoter in E. coli (Ki = 2 µM); produced during isomerase-dependent β-oxidation of oleic acid in isolated rat heart mitochondria
![Amsbio LLC Neuraminidase [Sialidase]; Acylneuraminyl hydrolase [EC 3.2.1.18]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502566247.png-250.jpg)
Amsbio LLC Neuraminidase [Sialidase]; Acylneuraminyl hydrolase [EC 3.2.1.18]
Neuraminidase [Sialidase]; Acylneuraminyl hydrolase [EC 3.2.1.18]
Enzo Life Sciences XAV939 (5 mg). CAS: 284028-89-3
Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM). Inhibition of tankyrase promotes stabilization of axin resulting in β-catenin degradation and Wnt signalling disruption. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells. Alternative name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (20 mg/ml). Long Term Storage: Ambient.
Cayman Chemical Oleoyl SerInol 5mg
An analog of ceramide and a GPR119 agonist (EC50 = 12 µM); induces cell death in F-11 murine neuroblastoma and U-87 human astrocytoma cells at 100 µM; induces apoptosis in rapidly dividing cells and prevents teratoma formation in a neonatal mouse engraftment model of teratoma formation
Cayman Chemical EthylmaLNyl Coenzyme AsodI 1mg
An intermediate in the ethylmalonyl-CoA pathway in bacteria
Cayman Chemical Oleoyl SerotonIn-d17 1mg
An internal standard for the quantification of oleoyl serotonin by GC- or LC-MS
Athens Research And Technology Inc KALLIKREIN HU PLASMA 50UG
Kallikrein, Human Plasma: 50 UG; Frozen in 20 mM Tris-HCl, pH 7.8, with 100 mM NaCl; MW 86,000-88,000; EC= 1.06; Activity: > =15 U/MG; Purity: > =95% by SDS-PAGE. Native; Prepared and purified from human plasma. Mol. Biology Reagent, Serine Protease
![Biolegend PerCP/Fire™ 780 anti-human CD4 [SK3]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502530554.png-250.jpg)
Biolegend PerCP/Fire™ 780 anti-human CD4 [SK3]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
PerCP/Fire™ 780 anti-human CD4 [SK3]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Cayman Chemical N-Oleoyl ValIn 25mg
An endogenous N-acyl amine; antagonist at TRPV3; increases after acute lung injury in mouse lung tissue